custom rat chemistry panel Search Results


4 plex cytokine elisa kit  (Quansys Biosciences)
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Quansys Biosciences 4 plex cytokine elisa kit
4 Plex Cytokine Elisa Kit, supplied by Quansys Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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custom rat chemistry panel  (IDEXX)
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IDEXX custom rat chemistry panel
Custom Rat Chemistry Panel, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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custom rat chemistry panel - by Bioz Stars, 2026-03
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msd multiplex assay, rat custom kidney injury panel  (Meso Scale Diagnostics LLC)
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Meso Scale Diagnostics LLC msd multiplex assay, rat custom kidney injury panel
Msd Multiplex Assay, Rat Custom Kidney Injury Panel, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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aimplex custom rat 10 plex panel fluorescence-based microbeads  (AimPlex Biosciences Inc)
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AimPlex Biosciences Inc aimplex custom rat 10 plex panel fluorescence-based microbeads
Aimplex Custom Rat 10 Plex Panel Fluorescence Based Microbeads, supplied by AimPlex Biosciences Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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milliplex map rat kidney toxicity magnetic bead panel 2  (Merck & Co)
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Merck & Co milliplex map rat kidney toxicity magnetic bead panel 2
Milliplex Map Rat Kidney Toxicity Magnetic Bead Panel 2, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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custom rat pro-inflammatory panel meso scale discovery kit  (Meso Scale Diagnostics LLC)
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Meso Scale Diagnostics LLC custom rat pro-inflammatory panel meso scale discovery kit
Custom Rat Pro Inflammatory Panel Meso Scale Discovery Kit, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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customized rat kidney injury panel  (Meso Scale Diagnostics LLC)
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Meso Scale Diagnostics LLC customized rat kidney injury panel
Diabetic ZSF1 rats recapitulate phenotypic changes of DKD with marked disease improvement by sGC activators (A) Representation of the importance of heme-containing (native) sGC and heme-free (dysfunctional) form of sGC and its redox equilibrium. sGC stimulator efficacy depends on the ferrous, Fe(II), state of the heme group at the β subunit of sGC, while sGC activators bind directly to oxidized, Fe(III), or heme-free apo form of sGC. Similar to other cardiovascular disorders, DKD is associated with reduced NO bioavailability, increased oxidative stress, and endothelial dysfunction. cGMP, cyclic guanosine monophosphate; DKD, diabetic <t>kidney</t> disease; NO, nitric oxide; NOS, nitric oxide synthase; O 2 − , superoxide; ONOO − , peroxynitrite; sGCact, soluble guanylate cyclase activator; sGCstim, soluble guanylate cyclase stimulator. Adapted from Sandner et al. (B) Experimental ZSF1 <t>rat</t> model setup. sGCact, soluble guanylate cyclase activator; sGCstim, sGC stimulator. (C–E) Metabolic (serum cholesterol, glucose, and plasma HbA1c) (C), kidney function (D), and kidney <t>injury</t> markers (E) after 12 study weeks; p values are given for either one-way ANOVA or Kruskal-Wallis test (both Benjamini, Krieger, Yekutieli corrected). Ob, obese; ns, not significant. Color legend as in (B). (F) Histopathology changes in hematoxylin/eosin (left) and Sirius red/fast green (right) stained kidney sections. Scale bars, 500 μm. (G) Histopathology scoring; p values are given for Kruskal-Wallis test (Benjamini, Krieger, Yekutieli corrected). Color legend as in (B).
Customized Rat Kidney Injury Panel, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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customized rat pro-inflammatory panel ii msd kit  (Meso Scale Diagnostics LLC)
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Meso Scale Diagnostics LLC customized rat pro-inflammatory panel ii msd kit
Diabetic ZSF1 rats recapitulate phenotypic changes of DKD with marked disease improvement by sGC activators (A) Representation of the importance of heme-containing (native) sGC and heme-free (dysfunctional) form of sGC and its redox equilibrium. sGC stimulator efficacy depends on the ferrous, Fe(II), state of the heme group at the β subunit of sGC, while sGC activators bind directly to oxidized, Fe(III), or heme-free apo form of sGC. Similar to other cardiovascular disorders, DKD is associated with reduced NO bioavailability, increased oxidative stress, and endothelial dysfunction. cGMP, cyclic guanosine monophosphate; DKD, diabetic <t>kidney</t> disease; NO, nitric oxide; NOS, nitric oxide synthase; O 2 − , superoxide; ONOO − , peroxynitrite; sGCact, soluble guanylate cyclase activator; sGCstim, soluble guanylate cyclase stimulator. Adapted from Sandner et al. (B) Experimental ZSF1 <t>rat</t> model setup. sGCact, soluble guanylate cyclase activator; sGCstim, sGC stimulator. (C–E) Metabolic (serum cholesterol, glucose, and plasma HbA1c) (C), kidney function (D), and kidney <t>injury</t> markers (E) after 12 study weeks; p values are given for either one-way ANOVA or Kruskal-Wallis test (both Benjamini, Krieger, Yekutieli corrected). Ob, obese; ns, not significant. Color legend as in (B). (F) Histopathology changes in hematoxylin/eosin (left) and Sirius red/fast green (right) stained kidney sections. Scale bars, 500 μm. (G) Histopathology scoring; p values are given for Kruskal-Wallis test (Benjamini, Krieger, Yekutieli corrected). Color legend as in (B).
Customized Rat Pro Inflammatory Panel Ii Msd Kit, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rat 4-plex custom panel  (Meso Scale Diagnostics LLC)
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Meso Scale Diagnostics LLC rat 4-plex custom panel
Diabetic ZSF1 rats recapitulate phenotypic changes of DKD with marked disease improvement by sGC activators (A) Representation of the importance of heme-containing (native) sGC and heme-free (dysfunctional) form of sGC and its redox equilibrium. sGC stimulator efficacy depends on the ferrous, Fe(II), state of the heme group at the β subunit of sGC, while sGC activators bind directly to oxidized, Fe(III), or heme-free apo form of sGC. Similar to other cardiovascular disorders, DKD is associated with reduced NO bioavailability, increased oxidative stress, and endothelial dysfunction. cGMP, cyclic guanosine monophosphate; DKD, diabetic <t>kidney</t> disease; NO, nitric oxide; NOS, nitric oxide synthase; O 2 − , superoxide; ONOO − , peroxynitrite; sGCact, soluble guanylate cyclase activator; sGCstim, soluble guanylate cyclase stimulator. Adapted from Sandner et al. (B) Experimental ZSF1 <t>rat</t> model setup. sGCact, soluble guanylate cyclase activator; sGCstim, sGC stimulator. (C–E) Metabolic (serum cholesterol, glucose, and plasma HbA1c) (C), kidney function (D), and kidney <t>injury</t> markers (E) after 12 study weeks; p values are given for either one-way ANOVA or Kruskal-Wallis test (both Benjamini, Krieger, Yekutieli corrected). Ob, obese; ns, not significant. Color legend as in (B). (F) Histopathology changes in hematoxylin/eosin (left) and Sirius red/fast green (right) stained kidney sections. Scale bars, 500 μm. (G) Histopathology scoring; p values are given for Kruskal-Wallis test (Benjamini, Krieger, Yekutieli corrected). Color legend as in (B).
Rat 4 Plex Custom Panel, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rat 4-plex custom panel/product/Meso Scale Diagnostics LLC
Average 90 stars, based on 1 article reviews
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Image Search Results


Diabetic ZSF1 rats recapitulate phenotypic changes of DKD with marked disease improvement by sGC activators (A) Representation of the importance of heme-containing (native) sGC and heme-free (dysfunctional) form of sGC and its redox equilibrium. sGC stimulator efficacy depends on the ferrous, Fe(II), state of the heme group at the β subunit of sGC, while sGC activators bind directly to oxidized, Fe(III), or heme-free apo form of sGC. Similar to other cardiovascular disorders, DKD is associated with reduced NO bioavailability, increased oxidative stress, and endothelial dysfunction. cGMP, cyclic guanosine monophosphate; DKD, diabetic kidney disease; NO, nitric oxide; NOS, nitric oxide synthase; O 2 − , superoxide; ONOO − , peroxynitrite; sGCact, soluble guanylate cyclase activator; sGCstim, soluble guanylate cyclase stimulator. Adapted from Sandner et al. (B) Experimental ZSF1 rat model setup. sGCact, soluble guanylate cyclase activator; sGCstim, sGC stimulator. (C–E) Metabolic (serum cholesterol, glucose, and plasma HbA1c) (C), kidney function (D), and kidney injury markers (E) after 12 study weeks; p values are given for either one-way ANOVA or Kruskal-Wallis test (both Benjamini, Krieger, Yekutieli corrected). Ob, obese; ns, not significant. Color legend as in (B). (F) Histopathology changes in hematoxylin/eosin (left) and Sirius red/fast green (right) stained kidney sections. Scale bars, 500 μm. (G) Histopathology scoring; p values are given for Kruskal-Wallis test (Benjamini, Krieger, Yekutieli corrected). Color legend as in (B).

Journal: Cell Reports Medicine

Article Title: Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution

doi: 10.1016/j.xcrm.2023.100992

Figure Lengend Snippet: Diabetic ZSF1 rats recapitulate phenotypic changes of DKD with marked disease improvement by sGC activators (A) Representation of the importance of heme-containing (native) sGC and heme-free (dysfunctional) form of sGC and its redox equilibrium. sGC stimulator efficacy depends on the ferrous, Fe(II), state of the heme group at the β subunit of sGC, while sGC activators bind directly to oxidized, Fe(III), or heme-free apo form of sGC. Similar to other cardiovascular disorders, DKD is associated with reduced NO bioavailability, increased oxidative stress, and endothelial dysfunction. cGMP, cyclic guanosine monophosphate; DKD, diabetic kidney disease; NO, nitric oxide; NOS, nitric oxide synthase; O 2 − , superoxide; ONOO − , peroxynitrite; sGCact, soluble guanylate cyclase activator; sGCstim, soluble guanylate cyclase stimulator. Adapted from Sandner et al. (B) Experimental ZSF1 rat model setup. sGCact, soluble guanylate cyclase activator; sGCstim, sGC stimulator. (C–E) Metabolic (serum cholesterol, glucose, and plasma HbA1c) (C), kidney function (D), and kidney injury markers (E) after 12 study weeks; p values are given for either one-way ANOVA or Kruskal-Wallis test (both Benjamini, Krieger, Yekutieli corrected). Ob, obese; ns, not significant. Color legend as in (B). (F) Histopathology changes in hematoxylin/eosin (left) and Sirius red/fast green (right) stained kidney sections. Scale bars, 500 μm. (G) Histopathology scoring; p values are given for Kruskal-Wallis test (Benjamini, Krieger, Yekutieli corrected). Color legend as in (B).

Article Snippet: With regard to biomarkers, all assays were performed according to manufacturers’ instructions: Plasma KIM-1 and neutrophil gelatinase-associated lipocalin (NGAL) were measured using a customized Rat Kidney Injury Panel (Meso Scale Discovery).

Techniques: Clinical Proteomics, Histopathology, Staining